:root {
    --teal: #2dc1b3;
    --teal-deep: #1a9589;
    --teal-dark: #0f6b63;
    --teal-pale: #e8f7f4;
    --teal-mist: #f4fbfa;
    --ink: #0b1f2a;
    --ink-2: #1a3340;
    --ink-3: #4a5d68;
    --ink-soft: #6f8089;
    --paper: #fafaf6;
    --paper-warm: #f5f2ec;
    --white: #ffffff;
    --line: #e6e7e3;
    --line-soft: #efeeea;
  }
  * { box-sizing: border-box; margin: 0; padding: 0; }
  html { scroll-behavior: smooth; }
  body {
    font-family: 'Geist', -apple-system, BlinkMacSystemFont, sans-serif;
    font-size: 16px; line-height: 1.55;
    color: var(--ink); background: var(--paper);
    -webkit-font-smoothing: antialiased; -moz-osx-font-smoothing: grayscale;
  }
  a { color: inherit; text-decoration: none; }
  img, svg { display: block; max-width: 100%; }
  .container { max-width: 1280px; margin: 0 auto; padding: 0 32px; }
  @media (max-width: 720px) { .container { padding: 0 20px; } }

  /* NAV */
  .nav { position: sticky; top: 0; z-index: 100; background: rgba(250, 250, 246, 0.85); backdrop-filter: saturate(150%) blur(14px); -webkit-backdrop-filter: saturate(150%) blur(14px); border-bottom: 1px solid var(--line-soft); }
  .nav-inner { display: flex; align-items: center; justify-content: space-between; padding: 16px 32px; max-width: 1400px; margin: 0 auto; }
  .logo-wrap { display: flex; align-items: center; gap: 10px; font-family: 'Libre Caslon Text', serif; font-weight: 500; font-size: 22px; letter-spacing: -0.02em; color: var(--ink); }
  .logo-mark { width: 34px; height: 34px; }
  .logo-wrap em { font-style: italic; color: var(--teal-deep); font-weight: 400; }
  .nav-links { display: flex; gap: 36px; font-size: 14.5px; color: var(--ink-2); }
  .nav-links a { position: relative; padding: 6px 0; transition: color 0.2s; }
  .nav-links a:hover { color: var(--teal-deep); }
  .nav-links a.active { color: var(--teal-deep); }
  .nav-links a.active::after { content: ''; position: absolute; bottom: 0; left: 0; right: 0; height: 1px; background: var(--teal); }
  .nav-cta { display: inline-flex; align-items: center; gap: 8px; padding: 10px 18px; background: var(--ink); color: var(--white); border-radius: 999px; font-size: 14px; font-weight: 500; transition: all 0.25s ease; }
  .nav-cta:hover { background: var(--teal-deep); transform: translateY(-1px); }
  .nav-cta::after { content: '→'; transition: transform 0.2s; }
  .nav-cta:hover::after { transform: translateX(3px); }
  @media (max-width: 960px) { .nav-links { display: none; } }

  /* BREADCRUMB */
  .breadcrumb { display: flex; align-items: center; gap: 10px; font-family: 'Geist Mono', monospace; font-size: 12px; letter-spacing: 0.1em; text-transform: uppercase; color: var(--ink-soft); margin: 60px 0 32px; flex-wrap: wrap; }
  .breadcrumb a { color: var(--teal-deep); transition: color 0.2s; }
  .breadcrumb a:hover { color: var(--ink); }
  .breadcrumb .sep { color: var(--line); }

  /* PILLS */
  .pill { font-family: 'Geist Mono', monospace; font-size: 11px; letter-spacing: 0.06em; padding: 4px 10px; border-radius: 999px; text-transform: uppercase; font-weight: 500; display: inline-block; }
  .pill-cleared { background: var(--teal-pale); color: var(--teal-dark); }
  .pill-breakthrough { background: #fef3e2; color: #a8640f; }
  .pill-trial { background: #f0eaff; color: #5b3fb8; }
  .pill-cpt { background: var(--ink); color: var(--teal); }
  .pill-foundation { background: #e8f0ff; color: #1e4599; }
  .pill-nature { background: var(--ink); color: #ffd27a; font-family: 'Libre Caslon Text', serif; font-style: italic; letter-spacing: 0.02em; font-size: 12px; }
  .pill-partnership { background: #f5e8ff; color: #7535c4; }
  .pill-reimbursement { background: #fff4e0; color: #8a5a1c; }

  /* PRODUCT HERO */
  .product-hero { display: grid; grid-template-columns: 1.35fr 1fr; gap: 72px; align-items: center; padding-bottom: 72px; border-bottom: 1px solid var(--line); margin-bottom: 72px; }
  @media (max-width: 960px) { .product-hero { grid-template-columns: 1fr; gap: 48px; padding-bottom: 56px; margin-bottom: 56px; } }
  .product-status { display: flex; gap: 10px; flex-wrap: wrap; margin-bottom: 24px; }
  .product-title { font-family: 'Geist', sans-serif; font-weight: 500; font-size: clamp(40px, 5.5vw, 64px); line-height: 1.02; letter-spacing: -0.035em; color: var(--ink); margin-bottom: 20px; }
  .product-title em { font-family: 'Libre Caslon Text', serif; font-weight: 350; font-style: italic; color: var(--teal-deep); font-variation-settings: 'SOFT' 80; }
  .product-tagline { font-size: 19px; line-height: 1.5; color: var(--ink-3); max-width: 540px; margin-bottom: 36px; }
  .product-hero-ctas { display: flex; gap: 12px; flex-wrap: wrap; }
  .btn-primary { display: inline-flex; align-items: center; gap: 10px; padding: 14px 24px; background: var(--ink); color: var(--white); border-radius: 999px; font-size: 15px; font-weight: 500; transition: all 0.25s ease; }
  .btn-primary:hover { background: var(--teal-deep); transform: translateY(-2px); box-shadow: 0 12px 28px -10px rgba(26, 149, 137, 0.5); }
  .btn-primary::after { content: '→'; transition: transform 0.2s; }
  .btn-primary:hover::after { transform: translateX(4px); }
  .btn-ghost { display: inline-flex; align-items: center; gap: 10px; padding: 14px 22px; background: transparent; color: var(--ink); border: 1px solid var(--line); border-radius: 999px; font-size: 15px; font-weight: 500; transition: all 0.2s; }
  .btn-ghost:hover { border-color: var(--ink); background: var(--white); }

  .product-visual { background: linear-gradient(145deg, var(--ink) 0%, #142834 100%); padding: 40px; border-radius: 24px; display: flex; align-items: center; justify-content: center; aspect-ratio: 1/1; max-width: 440px; margin-left: auto; position: relative; overflow: hidden; }
  .product-visual::before { content: ''; position: absolute; inset: 0; background: radial-gradient(circle at 70% 30%, rgba(45, 193, 179, 0.2), transparent 60%); }
  .product-visual svg { position: relative; z-index: 1; }

  /* PRODUCT BODY */
  .product-body { display: grid; grid-template-columns: 1fr 320px; gap: 72px; margin-bottom: 96px; align-items: start; }
  @media (max-width: 960px) { .product-body { grid-template-columns: 1fr; gap: 48px; } }

  .product-main > section { margin-bottom: 72px; }
  .product-main > section:last-child { margin-bottom: 0; }

  .section-tag { display: inline-flex; align-items: center; gap: 8px; font-size: 12px; letter-spacing: 0.18em; text-transform: uppercase; color: var(--teal-deep); font-weight: 500; margin-bottom: 18px; }
  .section-tag::before { content: ''; width: 24px; height: 1px; background: var(--teal); }
  .section-heading { font-family: 'Libre Caslon Text', serif; font-weight: 350; font-size: clamp(30px, 3.4vw, 40px); line-height: 1.05; letter-spacing: -0.025em; color: var(--ink); margin-bottom: 24px; }
  .section-heading em { font-style: italic; color: var(--teal-deep); font-weight: 300; }

  .prose { font-size: 17px; line-height: 1.7; color: var(--ink-2); max-width: 720px; }
  .prose p { margin-bottom: 1.2em; }
  .prose p:last-child { margin-bottom: 0; }
  .prose strong { font-weight: 600; color: var(--ink); }
  .prose em { font-style: italic; }

  /* STAT GRID */
  .stat-grid { display: grid; grid-template-columns: repeat(3, 1fr); gap: 1px; background: var(--line); border: 1px solid var(--line); border-radius: 18px; overflow: hidden; margin-top: 32px; }
  @media (max-width: 680px) { .stat-grid { grid-template-columns: repeat(2, 1fr); } }
  .stat-cell { background: var(--white); padding: 28px 24px; }
  .stat-value { font-family: 'Libre Caslon Text', serif; font-weight: 300; font-size: clamp(32px, 3.6vw, 44px); line-height: 1; letter-spacing: -0.02em; color: var(--ink); margin-bottom: 8px; }
  .stat-value em { font-style: italic; color: var(--teal-deep); }
  .stat-value small { font-family: 'Geist Mono', monospace; font-size: 13px; color: var(--teal-deep); margin-left: 4px; letter-spacing: 0.05em; }
  .stat-label { font-size: 13px; line-height: 1.45; color: var(--ink-3); }

  /* EVIDENCE LIST */
  .evidence-list { display: grid; gap: 14px; }
  .evidence-row { display: grid; grid-template-columns: 150px 1fr auto; gap: 20px; padding: 18px 22px; background: var(--white); border: 1px solid var(--line); border-radius: 14px; align-items: center; transition: all 0.2s; }
  .evidence-row:hover { border-color: var(--teal); background: var(--teal-mist); transform: translateY(-2px); }
  .evidence-row .journal { font-family: 'Libre Caslon Text', serif; font-style: italic; font-size: 16px; color: var(--teal-deep); }
  .evidence-row .title { font-size: 14.5px; color: var(--ink-2); line-height: 1.4; }
  .evidence-row .year { font-family: 'Geist Mono', monospace; font-size: 12.5px; color: var(--ink-soft); white-space: nowrap; }
  .evidence-row .ext { display: inline-block; margin-left: 6px; font-family: 'Geist Mono', monospace; font-size: 10.5px; color: var(--ink-soft); transition: color 0.2s; vertical-align: middle; }
  .evidence-row:hover .ext { color: var(--teal-deep); }
  @media (max-width: 680px) {
    .evidence-row { grid-template-columns: 1fr; gap: 4px; }
    .evidence-row .year { order: -1; }
  }

  /* SPEC TABLE */
  .spec-table { border: 1px solid var(--line); border-radius: 16px; overflow: hidden; background: var(--white); }
  .spec-row { display: grid; grid-template-columns: 200px 1fr; border-bottom: 1px solid var(--line-soft); padding: 18px 24px; gap: 20px; }
  .spec-row:last-child { border-bottom: 0; }
  .spec-label { font-family: 'Geist Mono', monospace; font-size: 11.5px; letter-spacing: 0.1em; text-transform: uppercase; color: var(--ink-soft); padding-top: 2px; }
  .spec-value { font-size: 15px; color: var(--ink-2); }
  .spec-value strong { color: var(--ink); font-weight: 600; }
  @media (max-width: 680px) { .spec-row { grid-template-columns: 1fr; gap: 4px; } }

  /* SIDEBAR AT-A-GLANCE */
  .product-aside {
    position: sticky; top: 100px;
    display: flex; flex-direction: column; gap: 20px;
  }
  @media (max-width: 960px) { .product-aside { position: static; } }
  .aside-card { background: var(--white); border: 1px solid var(--line); border-radius: 18px; padding: 24px 26px; }
  .aside-card h3 { font-family: 'Libre Caslon Text', serif; font-weight: 500; font-size: 17px; letter-spacing: -0.01em; color: var(--ink); margin-bottom: 16px; padding-bottom: 12px; border-bottom: 1px dashed var(--line); }
  .aside-list { list-style: none; display: grid; gap: 14px; }
  .aside-list li { font-size: 13.5px; line-height: 1.4; color: var(--ink-3); }
  .aside-list .item-label { display: block; font-family: 'Geist Mono', monospace; font-size: 10.5px; letter-spacing: 0.1em; text-transform: uppercase; color: var(--ink-soft); margin-bottom: 3px; }
  .aside-list .item-value { color: var(--ink); font-family: 'Libre Caslon Text', serif; font-size: 15px; letter-spacing: -0.01em; }
  .aside-card.dark { background: var(--ink); color: var(--white); border-color: var(--ink); }
  .aside-card.dark h3 { color: var(--white); border-bottom-color: rgba(255,255,255,0.15); }
  .aside-card.dark p { color: rgba(255,255,255,0.75); font-size: 14px; line-height: 1.5; margin-bottom: 14px; }
  .aside-card.dark a { display: inline-flex; align-items: center; gap: 6px; color: var(--teal); font-size: 13.5px; font-weight: 500; transition: gap 0.2s; }
  .aside-card.dark a:hover { gap: 10px; }

  /* RELATED PRODUCTS */
  .related-section { padding: 80px 0; background: var(--paper-warm); margin-top: 60px; }
  .related-header { margin-bottom: 40px; max-width: 720px; }
  .related-grid { display: grid; grid-template-columns: repeat(4, 1fr); gap: 16px; }
  @media (max-width: 900px) { .related-grid { grid-template-columns: repeat(2, 1fr); } }
  @media (max-width: 520px) { .related-grid { grid-template-columns: 1fr; } }
  .related-card { background: var(--white); border: 1px solid var(--line); border-radius: 16px; padding: 24px 22px; transition: all 0.25s; display: flex; flex-direction: column; gap: 12px; text-decoration: none; color: inherit; }
  .related-card:hover { border-color: var(--teal); transform: translateY(-3px); box-shadow: 0 14px 30px -16px rgba(11, 31, 42, 0.14); }
  .related-card h4 { font-family: 'Libre Caslon Text', serif; font-weight: 400; font-size: 20px; letter-spacing: -0.015em; line-height: 1.15; color: var(--ink); }
  .related-card h4 em { font-style: italic; color: var(--teal-deep); }
  .related-card p { font-size: 13.5px; line-height: 1.5; color: var(--ink-3); }
  .related-link { margin-top: auto; font-size: 12.5px; font-weight: 500; color: var(--teal-deep); font-family: 'Geist Mono', monospace; letter-spacing: 0.06em; text-transform: uppercase; display: inline-flex; align-items: center; gap: 4px; transition: gap 0.2s; }
  .related-card:hover .related-link { gap: 8px; }

  /* FOOTER CTA */
  .footer-cta { background: var(--ink); color: var(--white); border-radius: 24px; padding: 56px 48px; margin: 80px 0; display: grid; grid-template-columns: 1.3fr 1fr; gap: 40px; align-items: center; position: relative; overflow: hidden; }
  .footer-cta::before { content: ''; position: absolute; top: -50%; right: -20%; width: 70%; height: 200%; background: radial-gradient(ellipse, rgba(45, 193, 179, 0.22), transparent 60%); pointer-events: none; }
  .footer-cta > * { position: relative; z-index: 1; }
  @media (max-width: 820px) { .footer-cta { grid-template-columns: 1fr; padding: 40px 28px; gap: 28px; } }
  .footer-cta h2 { font-family: 'Libre Caslon Text', serif; font-weight: 340; font-size: clamp(28px, 3.2vw, 38px); line-height: 1.05; letter-spacing: -0.025em; color: var(--white); }
  .footer-cta h2 em { font-style: italic; color: var(--teal); font-weight: 300; }
  .footer-cta p { color: rgba(255,255,255,0.75); font-size: 15px; line-height: 1.55; margin-bottom: 20px; }
  .footer-cta a.btn-primary { background: var(--teal); color: var(--ink); }
  .footer-cta a.btn-primary:hover { background: var(--white); }

  /* FOOTER */
  footer { background: var(--paper); padding: 80px 0 40px; border-top: 1px solid var(--line); }
  .foot-grid { display: grid; grid-template-columns: 2fr 1fr 1fr 1fr; gap: 48px; margin-bottom: 64px; }
  @media (max-width: 860px) { .foot-grid { grid-template-columns: 1fr 1fr; gap: 32px; } }
  .foot-brand p { margin-top: 16px; color: var(--ink-3); font-size: 14.5px; max-width: 320px; line-height: 1.55; }
  .foot-col h5 { font-size: 12px; letter-spacing: 0.12em; text-transform: uppercase; color: var(--ink-soft); margin-bottom: 16px; font-weight: 500; }
  .foot-col ul { list-style: none; display: grid; gap: 10px; }
  .foot-col a { color: var(--ink-2); font-size: 14.5px; transition: color 0.2s; }
  .foot-col a:hover { color: var(--teal-deep); }

  .foot-compliance {
    padding: 28px 0;
    border-top: 1px solid var(--line);
    border-bottom: 1px solid var(--line);
    display: flex;
    align-items: center;
    justify-content: space-between;
    gap: 24px;
    flex-wrap: wrap;
    margin-bottom: 28px;
  }
  .compliance-label {
    font-family: 'Geist Mono', monospace;
    font-size: 11px;
    letter-spacing: 0.14em;
    text-transform: uppercase;
    color: var(--ink-soft);
  }
  .compliance-badges {
    display: flex;
    gap: 28px;
    flex-wrap: wrap;
    align-items: center;
  }
  .compliance-badge {
    display: inline-flex;
    align-items: center;
    gap: 8px;
    color: var(--ink-2);
    font-family: 'Geist Mono', monospace;
    font-size: 11.5px;
    letter-spacing: 0.08em;
    text-transform: uppercase;
  }
  .compliance-badge svg {
    color: var(--teal-deep);
    flex-shrink: 0;
  }
  .foot-bottom { padding-top: 28px; border-top: 1px solid var(--line); display: flex; justify-content: space-between; font-size: 13px; color: var(--ink-soft); flex-wrap: wrap; gap: 16px; }

/* DEIDENTIFICATION PAGE */

.deid-caption {
    padding: 14px 20px;
    font-family: 'Geist Mono', monospace;
    font-size: 11px;
    letter-spacing: 0.09em;
    text-transform: uppercase;
    color: rgba(255, 255, 255, 0.55);
    border-top: 1px solid rgba(255, 255, 255, 0.06);
    display: flex;
    justify-content: space-between;
    gap: 20px;
  }

.deid-caption .caption-tag { color: var(--teal); }

.deid-featured {
    background: var(--ink);
    border-radius: 20px;
    overflow: hidden;
    border: 1px solid var(--line);
    box-shadow: 0 20px 40px -24px rgba(11, 31, 42, 0.28);
    margin-bottom: 20px;
  }

.deid-featured img { width: 100%; height: auto; display: block; background: var(--ink); }

.deid-gallery {
    display: grid;
    grid-template-columns: repeat(3, 1fr);
    gap: 16px;
  }

.deid-lead { max-width: 740px; font-size: 17px; line-height: 1.65; color: var(--ink-3); margin-bottom: 36px; }

.deid-section { margin-bottom: 96px; }

.deid-tile {
    background: var(--ink);
    border-radius: 14px;
    overflow: hidden;
    border: 1px solid var(--line);
    box-shadow: 0 10px 20px -14px rgba(11, 31, 42, 0.2);
    transition: transform 0.2s, box-shadow 0.2s;
  }

.deid-tile .deid-caption { padding: 10px 14px; font-size: 10px; }

.deid-tile img { width: 100%; height: auto; display: block; background: var(--ink); }

.deid-tile:hover {
    transform: translateY(-2px);
    box-shadow: 0 16px 28px -16px rgba(11, 31, 42, 0.28);
  }